Estimation of polyclonal IgG4 hybrids in normal human serum
نویسندگان
چکیده
منابع مشابه
Tissue Distribution of 125I-human Nonspecific Polyclonal IgG in Normal and Induced Inflammation Mice
Many different radiolabeled antibodies have been used for radioimmunotherapy and radioimmunoscintigraphy of human diseases in animal experiments. In order to study the in vivo tissue distribution of antibody, we labeled human nonspecific polyclonal IgG with Na125I using chloramine-T method. An animal model was developed by injecting turpentine in the posterior left thigh of Balb/c mice. Tissue ...
متن کاملTissue Distribution of 125I-human Nonspecific Polyclonal IgG in Normal and Induced Inflammation Mice
Many different radiolabeled antibodies have been used for radioimmunotherapy and radioimmunoscintigraphy of human diseases in animal experiments. In order to study the in vivo tissue distribution of antibody, we labeled human nonspecific polyclonal IgG with Na125I using chloramine-T method. An animal model was developed by injecting turpentine in the posterior left thigh of Balb/c mice. Tissue ...
متن کاملProduction of serum proteins in normal diploid fibroblast-hepatoma cell hybrids and in A9-normal liver cell hybrids.
Two series of interspecific hybrids have been generated between liver cells (which actively secrete several serum proteins) and fibroblasts (which do not). In each series, one of the parental cells was a normal diploid cell: mouse hepatoma cells were fused with normal diploid rat fibroblasts, and normal rat liver cells were fused with mouse fibroblasts of the permanent line A9. The production o...
متن کاملRelatively restricted migration of polyclonal IgG4 may mimic a monoclonal gammopathy in IgG4-related disease.
OBJECTIVES IgG4-related disease (IgG4-RD) is an increasingly recognized syndrome of unknown etiology that can affect a wide variety of organs. The commonly shared features include tumor-like swelling of the involved organs, a lymphoplasmacytic infiltrate enriched with polyclonal IgG4-positive plasma cells, variable degree of fibrosis, and elevated serum concentrations of polyclonal IgG4. METH...
متن کاملPolyclonal hyperviscosity syndrome in IgG4-related disease and associated conditions
Polyclonal hyperviscosity syndrome (HVS) is rare and has been reported in various disorders of immune dysregulation and lymphoid hyperplasia. IgG4-Related Disease (IgG4-RD) is an emerging disorder often associated with exuberant hypergammaglobulinemia, and this review of seven cases establishes IgG4-RD as an important cause of polyclonal HVS.
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ژورنال
عنوان ژورنال: Immunology
سال: 2014
ISSN: 0019-2805
DOI: 10.1111/imm.12265